Publications

Our research

March, 2019 | EMBO Journal

Mutant Lef1 controls Gata6 in sebaceous gland development and cancer

Oulès B, Rognoni E, Hoste E, Goss G, Fiehler R, Natsuga K, Quist S, Mentink R, Donati G, Watt FM.

January, 2018 | Genome Biology

Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells

Ghahramani A, Donati G, Luscombe NM, Watt FM.

December, 2017 | Cell Stem Cell

Inflammation Training Prepares Skin Epithelial Stem Cells for Trauma

Proserpio V, Oliviero S, Donati G.

July, 2017 | Elife

Type XVII collagen coordinates proliferation in the interfollicular epidermis

Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuki S, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt FM, Shimizu H.

June, 2017 | Nat Cell Biol.

Wounding induces dedifferentiation of epidermal Gata6(+) cells and acquisition of stem cell properties

Donati G, Rognoni E, Hiratsuka T, Liakath-Ali K, Hoste E, Kar G, Kayikci M, Russell R, Kretzschmar K, Mulder KW, Teichmann SA, Watt FM.

March, 2017 | Nat Commun.

A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells

Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM.

May, 2016 | Genome Biology

Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation

Proserpio V, Piccolo A, Haim-Vilmovsky L, Kar G, Lönnberg T, Svensson V, Pramanik J, Natarajan KN, Zhai W, Zhang X, Donati G, Kayikci M, Kotar J, McKenzie AN, Montandon R, Billker O, Woodhouse S, Cicuta P, Nicodemi M, Teichmann SA.

March, 2016 | Immunol Cell Biol.

The niche in single-cell technologies

Donati G.

May, 2015 | Cell Stem Cell

Stem cell heterogeneity and plasticity in epithelia

Donati G, Watt FM.

January, 2015 | Nat Commun.

Innate sensing of microbial products promotes wound-induced skin cancer

Hoste E, Arwert EN, Lal R, South AP, Salas-Alanis JC, Murrell DF, Donati G, Watt FM.

October, 2014 | Stem Cell Reports

BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions

Kretzschmar K, Cottle DL, Donati G, Chiang MF, Quist SR, Gollnick HP, Natsuga K, Lin KI, Watt FM.

March, 2014 | Cell Stem Cell

Epidermal Wnt/Β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors

Donati G, Proserpio V, Lichtenberger BM, Natsuga K, Sinclair R, Fujiwara H, Watt FM.

February, 2013 | PNAS

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

Foijer F, DiTommaso T, Donati G, Hautaviita K, Xie SZ, Heath E, Smyth I, Watt FM, Sorger PK, Bradley A.

January, 2013 | Cell

Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination

Nardini M, Gnesutta N, Donati G, Gatta R, Forni C, Fossati A, Vonrhein C, Moras D, Romier C, Bolognesi M, Mantovani R.

June, 2012 | Nat Cell Biol.

Diverse epigenetic strategies interact to control epidermal differentiation

Mulder KW, Wang X, Escriu C, Ito Y, Schwarz RF, Gillis J, Sirokmány G, Donati G, Uribe-Lewis S, Pavlidis P, Murrell A, Markowetz F, Watt FM.

March, 2011 | PLoS One

NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters

Fossati A, Dolfini D, Donati G, Mantovani R.

February, 2011 | Cell

The basement membrane of hair follicle stem cells is a muscle cell niche

Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM.

July, 2010 | Nat Cell Biol.

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

Connelly JT, Gautrot JE, Trappmann B, Tan DW, Donati G, Huck WT, Watt FM.

April. 2008 | PLoS One

An NF-Y-dependent switch of positive and negative histone methyl marks on CCAAT promoters

Donati G, Gatta R, Dolfini D, Fossati A, Ceribelli M, Mantovani R.

April. 2005 | J Biol Chem.

Chromatin immunoprecipitation (ChIP) on chip experiments uncover a widespread distribution of NF-Y binding CCAAT sites outside of core promoters

Testa A, Donati G, Yan P, Romani F, Huang TH, Viganò MA, Mantovani R.